Treatment Adherence Pattern among HIV/AIDS Patients Receiving Treatment in the ART Centre of a Tertiary Hospital in Kolkata

Authors

  • Atanu Biswas KPC Medical College and Hospital, Kolkata, West Bengal, India
  • Asok Kumar Mandal KPC Medical College and Hospital, Kolkata, West Bengal, India

Keywords:

adherence pattern, HIV/AIDS, Antiretroviral therapy

Abstract

Background: WHO recommended at least 95% adherence to antiretroviral drugs for better outcome in terms of improved CD4 count, body weight, general well-being and decreased chance of drug resistance. This study was conducted with the objectives of describing socio-demographic profile and adherence pattern to ongoing regimens in adults with HIV/AIDS in a tertiary hospital in Kolkata, India.

Methods: An observational, descriptive cross-sectional study was conducted on the adults receiving ART treatment. Patients above 15 years of age, who received at least one year of treatment before the day of the interview, comprise the study population. Sample size was 279. Information regarding socio-demographic profiles and the level of adherence to treatment in last one month and last one year were collected. The subjects were also asked about the reason behind the missed doses.

Results: Majority of the subjects were male and belonged to 25-44 years of age group. Most of the subjects were from low socioeconomic status and had poor level of education. Adherence level of treatment in last one year was adequate in 93.9% subjects, whereas 98.6% subjects had adequate adherence level in last one month. Fear of side effects from the drugs and forgetfulness were the major reasons behind the missed doses.

Conclusion: Emphasis should be given on awareness generation and proper counseling of the people with HIV/AIDS so as to maintain adequate adherence level of therapy improving their general well-being.

References

Bhalwar R. Textbook of Public Health and Community Medicine. 1st Ed. Pune: AFMC ; 2009. 1163-73.

Global AIDS Update 2016. UNAIDS. Joint United Na-tions Programme on HIV/AIDS. Geneva. [cited 29th July 2016]. Available from: www.unaids.org

Taneja DK. Health Policies and Programmes in India. National AIDS Control Programme. 14th ed. Delhi: Doc-tors Publication; 2016. p. 303.

Annual Report (2013-14), National AIDS Control Organ-ization. Ministry of Health and Family Welfare. Govern-ment of India, New Delhi.

India HIV estimation 2015. Technical Report. National AIDS Control Organization. Ministry of Health and Family Welfare. Government of India, New Delhi.

HIV/AIDS : Care for Nutrition, Care and Support. Food and Nutrition technical Assistance. USAID. July 2001. [cited 29th July 2016] Available from : http://www.who.int/ hac/techguidance/pht/8518.pdf

Achappa B, Madi D, Bhaskaran U, Ramapuram J T, RaoSatish, Mahalingam S. Adherence to antiretroviral therapy among people living with HIV. National Ameri-can Journal of Medical ScienceMarch 3013; 5(3): 220-3.

Lal V, Kant S, Dewan R, Rai S K, Biswas A. A two-site hospital-based study on factors associated with non-adherence to highly active antiretroviral therapy. Indian Journal of Public Health. Dec 2010; 54(4).

Shah B, Walshe L, Saple DG et al. Adherence to antiretro-viral therapy and virologic suppression among HIV-infected persons receiving care in private clinics in Mum-bai, India 2007. Clinical Infectious Diseases; 44 (9): 1235–44.

Pujari S, Patel A, Joshi S R, Gangakhedkar R, Ku-marasamy N, Gupta S B. Guidelines for Use of An-tiretroviral Therapy for HIV Infected Individuals in India (ART Guidelines 2008) .JAPI. May 2008; 56: 339-72.

Wanchu A, Kaur R, Bambery P, Singh S. Adherence to generic reverse transcriptase inhibitor-based antiretroviral medication at a Tertiary Center in North India. AIDS Be-hav. 2007; 11:99–102.

Sharma M, Singh RR, Laishram P, Kumar B, Nanao H, Sharma C et al. Access, adherence, quality and impact of ARV provision to current and ex-injecting drug users in Manipur (India): an initial assessment. International Journal of Drug Policy. 2007 Aug; 18(4):319-25.

Khan M A, Sehgal A. Clinico-epidemiological and socio-behavioral study of people living with HIV/AIDS. Indian Journal of Psychological Medicine. 2010; 32 (1): 22-8.

Tull L, Mohapatra T M, Gulati A K. Socio economic rele-vance of opportunistic infections in HIV patients in & around Varanasi. Indian journal of Preventive & social medicine. 2008; 39 (1&2): 33-5.

Sarna A, Pujari S, Sengar AK, Garg R, Gupta I. Adher-ence to antiretroviral therapy & its determinants among HIV patients in India. Indian Journal of Medical research. 2008 Jan; 127: 28-36.

Sinha S, Bhattacharya M, Adhish S V. A cross-sectional study on adherence to anti-retrovirals among HIV/AIDS patients in Delhi under the national ART programme. Health and population –Perspectives and Issues 2011; 34 (20): 87-106.

Mhaskar R, Alandikar V, Emmanuel P, Djulbegovic B, Patel S, Patel A, Naik E, Mohapatra S, Kumar A. Adher-ence to antiretroviral therapy in India: A systematic re-view and meta-analysis. Indian Journal of Community Medicine. 2013 [cited 2014 Sep 24]; 38: 74-82.

Safren SA, Kumarasamy N, James R, Raminani S, Solo-mon S, Mayer KH et al. ART adherence, demographic variables and CD4 outcome among HIV-positive patients on antiretroviral therapy in Chennai, India. AIDS Care. 2005 Oct; 17(7):853-62.

Downloads

Published

2016-11-30

How to Cite

1.
Biswas A, Mandal AK. Treatment Adherence Pattern among HIV/AIDS Patients Receiving Treatment in the ART Centre of a Tertiary Hospital in Kolkata. Natl J Community Med [Internet]. 2016 Nov. 30 [cited 2024 May 3];7(11):873-7. Available from: https://www.njcmindia.com/index.php/file/article/view/1084

Issue

Section

Original Research Articles