Assessment of Barriers in Initiation and Completion of Isoniazid Preventive Therapy among Household Child Con-tacts of Pulmonary TB Patients in Delhi: A Mixed Method Study

Authors

  • Faheem Ahmed HIMSR, New Delhi
  • Tazean Zahoor Malik HIMSR, New Delhi
  • Farzana Islam HIMSR, New Delhi
  • Areeba Muzaffar HIMSR, New Delhi

DOI:

https://doi.org/10.5455/njcm.20200611114058

Keywords:

Household contact, isoniazid, preventive therapy, pulmonary tuberculosis

Abstract

Background: Young children (aged < 6 years) in contact with Sputum positive TB adults are often infected with Mycobacterium tuberculosis and once infected are at higher risk of progression to TB disease than adults.

Objectives: The study was conducted To find out the proportion of < 6 years of age children having household contact of a pulmonary TB patient, screened, initiated, and completed IPT in the year 2019 and to find out the barriers for not completing/taking IPT.

Methodology: A mixed-method study was conducted during July–September 2019 among household contacts of < 6 years of age of sputum positive pulmonary TB patients attending a DOT centre in South – East Delhi.

Results: A total of 52 household contacts of less than 6 years of age were identified. Whereas 65% of the study population was aware of IPT, only 26.9% of individuals were on IPT out of the total study population and only 4 % had completed the IPT. On qualitative analysis, most of them informed that the DOTS provider didn’t emphasize them about IPT. Some of them felt that it isn’t required since the child does not have the disease.

Conclusion: Adherence to IPT is low. The dearth of IEC activities in the study area adds to this burden. Hence prompt IEC activities and adequate training of DOT providers for initiation and adherence of IPT is the need of the time.

References

Global tuberculosis report 2019. Geneva: World Health Or-ganization; 2019. License: CC BY-NC-SA 3.0 IGO.

Beyers N, Gie RP, Schaaf HS, Van Zyl S, Talent JM, Nel ED, et.al. A prospective evaluation of children under the age of 5 years living in the same household as adults with recently diagnosed pulmonary tuberculosis. Int J Tuberc Lung Dis 1997;1:38–43.

Marais BJ, Gie RP, Schaaf HS, Hesseling AC, Obihara CC, Starke JJ, et.al. The natural history of childhood intra-thoracic tuberculosis: a critical review of literature from the pre-chemotherapy era [State of the Art]. Int J Tuberc Lung Dis. 2004 Apr 1;8(4):392-402

Stop TB Partnership Childhood TB Subgroup (2007) Chap-ter 4: childhood contact screening and management. Int J Tuberc Lung Dis 11: 12–15. [cited 2020 Jun 11]

World Health Organisation, Geneva (2006) Guidance for National Tuberculosis Programmes on the Management of Tuberculosis in Children. [cited 2020 Jun 11]

World Health Organization. Guidance for national tubercu-losis programmes on the management of tuberculosis in children. WHO; Geneva, Switzerland: 2006. WHO/HTM/ TB/2006.371 [cited 2020 Jun 11]

Shivaramakrishna HR, Fredrick A, Shazia A, Murali L, Satyanarayana S, Nair SA et. al. Isoniazid preventive treat-ment in children in two districts of South India: does prac-tice follow policy? Int J Tuberc Lung Dis. 2014 Aug; 18(8):919–24. [cited 2020 Jun 11] doi:10.5588/ijtld.14.0072.

Osman M, Hesseling AC, Beyers N, Enarson DA, Rusen ID, Lombard C, et.al. Routine programmatic delivery of isonia-zid preventive therapy to children in Cape Town, South Af-rica. Public Health Action 2013 Sep 21;3:199-203

Pothukuchi M, Nagaraja SB, Kelamane S, Satyanarayana S, Shashidhar, Babu S, et al. Tuberculosis Contact Screening and Isoniazid Preventive Therapy in a South Indian District: Operational Issues for Programmatic Consideration. PLoS ONE 6(7): e22500. [cited 2020 Jun 11] doi:10.1371/ jour-nal.pone.0022500

Singh AR, Kharate A, Bhat P, Kokane AM, Bali S, Sahu S et al. Isoniazid Preventive Therapy among Children Living with Tuberculosis Patients: Is It Working? A Mixed Method Study from Bhopal, India. Journal of Tropical Pediatrics 201:63;274–85

Hall C, Sukijthamapan P, dos Santos R, et al. Challenges to delivery of isoniazid preventive therapy in a cohort of chil-dren exposed to tuberculosis in Timor-Leste. Trop Med Int Health 2015;20:730–6

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Published

2020-05-31

How to Cite

1.
Ahmed F, Malik TZ, Islam F, Muzaffar A. Assessment of Barriers in Initiation and Completion of Isoniazid Preventive Therapy among Household Child Con-tacts of Pulmonary TB Patients in Delhi: A Mixed Method Study. Natl J Community Med [Internet]. 2020 May 31 [cited 2024 Mar. 28];11(05):227-31. Available from: https://www.njcmindia.com/index.php/file/article/view/306

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Original Research Articles