Antimicrobial Susceptibility Pattern of Bacterial Isolates from Urine Samples from Female Patients Suffering From Urinary Tract Infection at Tertiary Care Center in South India

Vidya KR; Meghana  Manjunath; Lohit K; Prashanth HV

doi:10.5455/njcm.20210602064325

Authors

Vidya KR Shri Atal Bihari Vajpayee Medical College & Research Institute, Bengaluru, Karnataka
Meghana Manjunath Sri Siddhartha Medical College, Tumkur, Karnataka
Lohit K Sri Siddhartha Institute of Medical Sciences & Research Centre, T Begur. Nelamangala. Bangalore, Karnataka
Prashanth HV Sri Siddhartha Medical College. Tumkur, Karnataka

DOI:

https://doi.org/10.5455/njcm.20210602064325

Keywords:

Urinary tract Infection, Antimicrobial susceptibility, Bacterial infection, Bacteriuria

Abstract

Introduction: The frequency of bacteria affecting urinary tract and their antibiotic susceptibility pattern vary from one territory to another. This study was conducted to determine spectrum of bacterial isolates causing UTI and their antibiotic susceptibility pattern among female patients attending tertiary care center

Materials and Methods: A total of 577 female urine culture sensitivity reports (CS) were collected. The culture was done by inoculation by standard loop technique. Antibiotic susceptibility testing for identified bacteria was done by Kirby-Bauer disc diffusion method and result was interpreted as per CLSI guidelines. Data was analyzed using SPSS software.

Results: Infection rates were similar up to reproductive age group with no significant difference between gram-positive (GP) and gram-negative organisms (GN) but post reproductive age group suffered more from GN. The most commonly infecting organism was Staphylococci followed by Escherichia coli showing resistance in >50% tests to cephalosporins, penicillin and fluoroquinolones. All antibiotics are showing resistance from one or the other organisms.

Conclusion: The commonly infecting bacteria are developing resistance to regularly used antibiotics raising concerns of cross resistance and selection of antibiotics. This warrants due diligence by all stakeholders, including public-health authorities, health care providers, policymakers and even the public to prevent and control antimicrobial resistance.

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