Evaluation of Clinico-Demographic Profile and Survival Rate among Patients of Head and Neck Cancer

Authors

  • Anand Shah Gujarat Cancer Research Institute, Ahmedabad
  • Ravi Patel Shantabaa Medical College and General Hospital, Amreli
  • Shashank Pandya Gujarat Cancer Research Institute, Ahmedabad
  • Jayesh Solanki Gujarat Cancer Research Institute, Ahmedabad
  • Vaishali Ravani Gujarat Cancer Research Institute, Ahmedabad

DOI:

https://doi.org/10.55489/njcm.1342022439

Keywords:

Head & Neck Cancer, Clinical profile, demographic profile, survival rate

Abstract

Background: Head and Neck cancer (HNC) is a recognized major public health concern all over the world
Objectives: To study age and gender predilection and clinical profile of Head & Neck Cancers
Materials and Methods: This was a retrospective study including 21121 patients with Head & Neck Cancer presented to tertiary care centre, Ahmadabad. Patients' details of age, sex, site of carcinoma, stage at presentation and Outcome were recorded. The data was analyzed using MS office excel 2010 and Epi info software version 7.0.
Result: Male to female ratio was 4.8:1. The most common site of presentation of tumour was in cheek mucosa (29.01 %). On comparison of different anatomical sites, majority of patients were presented in locally advanced stage. Significant association (p<0.05) was found between presentation of disease and literacy status. Overall 5 - year survival rate was 60.5% ± 1.6% when disease was localized.
Conclusion: Majority of patients diagnosed in locally advanced stage. Strategies for the early diagnosis and prevention of Head & Neck cancer must be undertaken by government to overcome this situation.

References

Narayana Health. A detailed guide about Head and Neck Cancers. Available from :https://www.narayanahealth.org/blog/a-detailed-guide-about-head-and-neck-cancers/ [Accessed 11th March 2021]

Cancer.Net. Head and Neck Cancer: Introduction. Available from: https://www.cancer.net/cancer-types/head-and-neck-cancer/introduction [Accessed 11thMarch 2021]

Argirion I, Zarins K, Defever K, et al. Temporal Changes in Head and Neck Cancer Incidence in Thailand Suggest Changing Oropharyngeal Epidemiology in the Region. Journal of Global Oncology. 2019;5. Available from: https://doi.org/10.1200/JGO.18.00219

Oncology//PRO. Clinical features and survival rates. Available from: https://oncologypro.esmo.org/education-library/essentials-for-clinicians/head-neck-cancers/clinical-features-and-survival-rates [Accessed 11th March 2021]

National Cancer Institute. Cancer Staging. Available from: https://www.cancer.gov/about-cancer/diagnosis-staging/staging [Accessed 11th March 2021]

Alam M, Siddiqui S, Perween R. Epidemiological profile of head and neck cancer patients in Western Uttar Pradesh and analysis of distributions of risk factors in relation to site of tumor. Journal of Cancer Research and Therapeutic. 2017;13(3): 430-435. Available from: https://doi.org/10.4103/0973-1482.180687

Cancer. Net. Head and Neck Cancer: Risk Factors and Prevention. Available from:https://www.cancer.net/cancer-types/head-and-neck-cancer/risk-factors-and-prevention [Accessed 15thApril 2021]

National Cancer Institute. Head and Neck Cancers. Available from : https://www.cancer.gov/types/head-and-neck/head-neck-fact-sheet#what-are-the-symptoms-of-head-and-neck-cancers [Accessed 15thApril 2021]

Addala L, Pentapati C, Thavanati PK, et al. Risk factor profiles of head and neck cancer patients of Andhra Pradesh, India. Indian Journal of Cancer. 2012; 49(2): 215-219.Availablefrom: http://www.indianjcancer.com/article.asp?issn=0019-509X;year=2012;volume=49;issue=2;spage=215;epage=219;aulast=Addala [Accessed 15thApril 2021]

Global Adult Tobacco Survey-2. Global adult tobacco survey Fact sheet/Gujarat. Available from: https://tmc.gov.in/images/act/Gujarat%20GATS-2%20Factsheet.pdf [Accessed 17thApril 2021]

Gilyoma J, Rambau P, Masalu N, et al. Head and neck cancers: a clinico-pathological profile and management challenges in a resource-limited setting. BMC Research Notes. 2015;8. Available from: https://doi.org/10.1186/s13104-015-1773-9

K. Park. Epidemiology of chronic non-communicable diseases and conditions. In: K. Park (ed), Park’s textbook of Preventive and Social Medicine. 25th edition. Jabalpur, India: M/s Banarsidas Bhanot; 2019. 417.

Novin K, Ameri A, Faraji S, et al. Head and Neck Squamous Cell Carcinoma in Iran: Clinico-Pathological and Treatment-Related Factors Influencing Survival. Iranian Journal of Cancer Prevention. 2015;8(5). Available from: https://doi.org/10.17795/ijcp-3842

Saxena P, Unnikrishnan B, Rathi P, et al. Survival analysis of head and neck cancer: Results from a hospital based cancer registry in southern Karnataka. Clinical Epidemiology and Global Health. 2019;7:346-350. Available from: https://doi.org/10.1016/j.cegh.2018.08.007

Pruegsanusak K, Peeravut S, Leelamanit V, et al. Survival and Prognostic Factors of Different Sites of Head and Neck Cancer: An Analysis from Thailand. Asian Pacific Journal of Cancer Prevention. 2012; 13: 885-890. Available from: http://dx.doi.org/10.7314/APJCP.2012.13.3.885

Downloads

Published

2022-04-30

How to Cite

1.
Shah A, Patel R, Pandya S, Solanki J, Ravani V. Evaluation of Clinico-Demographic Profile and Survival Rate among Patients of Head and Neck Cancer. Natl J Community Med [Internet]. 2022 Apr. 30 [cited 2024 Apr. 26];13(04):248-52. Available from: https://www.njcmindia.com/index.php/file/article/view/439

Issue

Section

Original Research Articles