Quantitative Study of Factors Associated with Breast Cancer among Women Reporting to a Tertiary Care Hospital in Karnataka

Authors

  • Venkatesh Gonibeedu HIMS Hassan, Hassan
  • Vamsi Kakileti HIMS Hassan, Hassan

DOI:

https://doi.org/10.5455/njcm.20200609092021

Keywords:

Breast cancer, menarche, parity, age at first birth

Abstract

Introduction: Numerous epidemiological studies performed throughout the world have confirmed the role of many risk factors. However, evidence suggests that international variation in the burden of breast cancer reflects differences in the patterns of risk factors. Hence this study is undertaken to assess the risk factors associate with breast cancer in a district in Karnataka.

Method: This is a Case control study to assess the risk factors associated with breast cancer among cases attending radiation unit of Hassan institute of medical sciences during 2019.

Results: There was a significant association of breast cancer with menarche attained at or less than age 13 years (OR=2.43, CI: 1.09-5.4, p<0.029), usage of oral contraceptive (OR=2.04: CI 1.61-2.42; p<0.1), and menopause attained before age 50 (OR=5.2: CI2.2-12.2; p<0.00). Our study also found that for every year increase in age for 1st birth, controls not being diseased decreased by 26% was statistically significant (OR=0.76; CI:0.61-0.89; p<0.002) and for every parity added, controls not being deceased increased by 1.13 time (OR=1.13; CI:0.69-1.8;p<0.6).

Conclusion: District cancer control programme should advice women, to consume non-vegetarian food in moderation, promote physical activity form early age to maintain ideal body mass index.

References

Globocan (2018): http://globocan.iarc.fr/Pages/fact_ sheets_cancer.aspx. Accessed on March 21st 2020

Lê MG, Bachelot A, Hill C (1989). Characteristics of repro-ductive life and risk of breast cancer in a case-control study of young nulliparous women. J Clin Epidemiology. 42(12): 1227-33

Vieira R, Tobar JSS, Dardes R, Claudio L, Thuler S (2018). Alcohol Consumption as a Risk Factor for Breast Cancer Development: A Case-control study in Brazil. Asian Pac J Cancer Prevention; 27;19(3):703-707

Gjorgov AN(1978). Barrier contraceptive practice and male infertility as related factors to breast cancer in married women. Preliminary results. Oncology.35(3):97-100

M.P. Vessey, K. McPherson, M.M. Roberts, A. Neill & L. Jones (1985). Fertility in relation to the risk of breast cancer. Br. J. Cancer,52, 625-628

Winters S, Martin C, Murphy D, Shokar NK (2017). Breast Cancer Epidemiology, Prevention, and Screening Prog Mol Biol Transl Sci. 51:1-32.

DeSantis CE, Bray F, Ferlay J, Lortet-Tieulent J, Anderson BO, Jemal A (2015). International Variation in Female Breast Cancer Incidence and Mortality Rates. Cancer Epidemiolo-gy Biomarkers & Prevention;24(10):1495–1506

Leon Guerrero RT, Novotny R, Wilkens LR, Chong M, White KK, Shvetsov YB, et al (2017). Risk factors for breast cancer in the breast cancer risk model study of Guam and Saipan. Cancer Epidemiol. 50(Pt B):221-233

Park B, Hopper JL, Win AK, Dowty JG, Sung HK, Ahn C et al. (2017). Reproductive factors as risk modifiers of breast cancer in BRCA mutation carriers and high-risk non-carriers. Onco target. ; 31;8(60):110-118

Terry MB, Tehranifar P (2013). Hormone replacement thera-py and breast cancer risk: More evidence for risk stratifica-tion? J Natl Cancer Inst. 105(18):1342–1343

Se-Eun Lim , HyoJin Ahn , Eun Sook Lee, Sun-Young Kong, So-Youn Jung , Seeyoun Lee et al.( 2019). Interaction Effect Between Breast Density and Reproductive Factors on Breast Cancer Risk in Korean Population. J Cancer Prev ;24(1):26-32.

Khalis M, Charbotel B, Chajes V, Rinaldi S, Moskal A, Biessy C, et al. (2018) Menstrual and reproductive factors, and risk of breast cancer. A Case-control study in the Fez region, morocco. PLos One ;16(13);1-12

Shuyuasa, Bbrian-macmahon1(970). Lactation and Repro-ductive Histories of Breast Cancer Patients in Tokyo, Japan. Bull. World Health Org, 42, 195-204

Ambrosone CB, Zirpoli G, Ruszczyk M, et al (2014). Parity and breastfeeding among African American women: Differ-ential effects on breast cancer risk by estrogen receptor sta-tus in the Women's Circle of Health Study. Cancer Causes Control;25(2):259–265

Downloads

Published

2020-06-30

How to Cite

1.
Gonibeedu V, Kakileti V. Quantitative Study of Factors Associated with Breast Cancer among Women Reporting to a Tertiary Care Hospital in Karnataka. Natl J Community Med [Internet]. 2020 Jun. 30 [cited 2024 Apr. 23];11(06):244-7. Available from: https://www.njcmindia.com/index.php/file/article/view/317

Issue

Section

Original Research Articles